This tablets 1mg contain ketotifen, an antihistamine that also has anti-allergy property and is used for prophylaxis for asthma, as non-bronchodilator anti-asthmatic medicine, as well as treatment for a few allergies. Ketotifen in Ketasma 1mg pills are thought to work by acting as a histamine antagonist and binding to the H1 receptor, which blocks the histamine-mediated near the beginning phase of the allergic response, in which little blood vessels grow leaky cause tissue swelling and irritant as well as reduce the migration of inflammatory cell.

Ketotifen inhibits the free of inflammatory chemicals including histamine, leukotrienes, and prostaglandins also platelet activating factor (PAF), the chief mediator of bronchoconstriction (narrowing of the airways). By blocking the histamine H1 receptor, the generic drug of ketotifen prevents the improvement of the hyperactive airway that occurs in asthma and decreases the symptoms of allergic rhinitis caused by the actions of histamine. This medicine is sedating antihistamine as it binds to H1 receptors in blood vessels and the central nervous system.